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microRNA-99a Restricts Replication of Hepatitis C Virus by Targeting mTOR and De Novo Lipogenesis
In this study, we investigated the role of microRNA-99a (miR-99a) in hepatitis C virus (HCV) replication and lipogenesis in hepatocytes. Cell-culture-derived HCV (HCVcc) infection caused down-regulation of miR-99a in Huh-7 cells, and the relative levels of miR-99a were significantly lower in the ser...
Autores principales: | Lee, Eun Byul, Sung, Pil Soo, Kim, Jung-Hee, Park, Dong Jun, Hur, Wonhee, Yoon, Seung Kew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411587/ https://www.ncbi.nlm.nih.gov/pubmed/32605105 http://dx.doi.org/10.3390/v12070696 |
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