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aBravo Is a Novel Aedes aegypti Antiviral Protein That Interacts with, but Acts Independently of, the Exogenous siRNA Pathway Effector Dicer 2

Mosquitoes, such as Aedes aegypti, can transmit arboviruses to humans. The exogenous short interfering RNA (exo-siRNA) pathway plays a major antiviral role in controlling virus infection in mosquito cells. The Dicer 2 (Dcr2) nuclease is a key effector protein in this pathway, which cleaves viral dou...

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Detalles Bibliográficos
Autores principales: Varjak, Margus, Gestuveo, Rommel J., Burchmore, Richard, Schnettler, Esther, Kohl, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411624/
https://www.ncbi.nlm.nih.gov/pubmed/32664591
http://dx.doi.org/10.3390/v12070748