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Simple water‐based tacrolimus enemas for refractory proctitis

BACKGROUND AND AIMS: Rectal ulcerative colitis (UC) and Crohn's disease (CD) often do not respond to conventional therapies. Oral and suppository tacrolimus are effective but often poorly tolerated or are complex to formulate. Tacrolimus is topically active, water soluble, and has minimal syste...

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Detalles Bibliográficos
Autores principales: Fehily, Sasha R., Martin, Felicity C., Kamm, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411644/
https://www.ncbi.nlm.nih.gov/pubmed/32782938
http://dx.doi.org/10.1002/jgh3.12280