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Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study

In this study, a specific and sensitive method of liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was developed for the determination of penconazole enantiomers in rat plasma. The enantioseparation was achieved on a Chiralpak IC column by using acetonitrile/water (80:20, v/v)...

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Detalles Bibliográficos
Autores principales: Ma, Siman, Lun, Jia, Liu, Yanru, Jiang, Zhen, Guo, Xingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411863/
https://www.ncbi.nlm.nih.gov/pubmed/32605157
http://dx.doi.org/10.3390/molecules25132964