New Paracyclophanylthiazoles with Anti-Leukemia Activity: Design, Synthesis, Molecular Docking, and Mechanistic Studies

A new series of methyl 2-(2-(4′-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates 3a–f were synthesized from the reaction of paracyclophanyl-acylthiosemicarbazides 2a–f with dimethyl acetylenedicarboxylate. Based upon nuclear magnetic resonance (NMR), infrared...

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Detalles Bibliográficos
Autores principales: Aly, Ashraf A, Bräse, Stefan, Hassan, Alaa A., Mohamed, Nasr K., Abd El-Haleem, Lamiaa E., Nieger, Martin, Morsy, Nesrin M., Abdelhafez, Elshimaa M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411887/
https://www.ncbi.nlm.nih.gov/pubmed/32645912
http://dx.doi.org/10.3390/molecules25133089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411887/
https://www.ncbi.nlm.nih.gov/pubmed/32645912
http://dx.doi.org/10.3390/molecules25133089

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