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Acidic pH Triggers Lipid Mixing Mediated by Lassa Virus GP

Lassa virus (LASV) is the causative agent of Lassa hemorrhagic fever, a lethal disease endemic to Western Africa. LASV entry is mediated by the viral envelope glycoprotein (GP), a class I membrane fusogen and the sole viral surface antigen. Previous studies have identified components of the LASV ent...

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Detalles Bibliográficos
Autores principales: Bulow, Uriel, Govindan, Ramesh, Munro, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411951/
https://www.ncbi.nlm.nih.gov/pubmed/32630688
http://dx.doi.org/10.3390/v12070716