Pharmacokinetics and Metabolism of Liposome-Encapsulated 2,4,6-Trihydroxygeranylacetophenone in Rats Using High-Resolution Orbitrap Liquid Chromatography Mass Spectrometry

2,4,6-trihydroxy-3-geranylacetophenone (tHGA) is a bioactive compound that shows excellent anti-inflammatory properties. However, its pharmacokinetics and metabolism have yet to be evaluated. In this study, a sensitive LC-HRMS method was developed and validated to quantify tHGA in rat plasma. The me...

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Detalles Bibliográficos
Autores principales: Alkhateeb, Yamen, Jarrar, Qais Bashir, Abas, Faridah, Rukayadi, Yaya, Tham, Chau Ling, Hay, Yuen Kah, Shaari, Khozirah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412073/
https://www.ncbi.nlm.nih.gov/pubmed/32640512
http://dx.doi.org/10.3390/molecules25133069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412073/
https://www.ncbi.nlm.nih.gov/pubmed/32640512
http://dx.doi.org/10.3390/molecules25133069

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