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Pharmacokinetics and Metabolism of Liposome-Encapsulated 2,4,6-Trihydroxygeranylacetophenone in Rats Using High-Resolution Orbitrap Liquid Chromatography Mass Spectrometry
2,4,6-trihydroxy-3-geranylacetophenone (tHGA) is a bioactive compound that shows excellent anti-inflammatory properties. However, its pharmacokinetics and metabolism have yet to be evaluated. In this study, a sensitive LC-HRMS method was developed and validated to quantify tHGA in rat plasma. The me...
Autores principales: | Alkhateeb, Yamen, Jarrar, Qais Bashir, Abas, Faridah, Rukayadi, Yaya, Tham, Chau Ling, Hay, Yuen Kah, Shaari, Khozirah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412073/ https://www.ncbi.nlm.nih.gov/pubmed/32640512 http://dx.doi.org/10.3390/molecules25133069 |
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