The Mutation of the Genes Related to Neurovirulence in HSV-2 Produces an Attenuated Phenotype in Mice

HSV-2 (Herpes simplex virus type 2) is a critical viral agent that mainly causes genital herpes and life-long latent infection in the dorsal root ganglia. Gene modification via CRISPR/Cas9 Clustered regularly interspaced short palindromic repeat sequences/CRISPR associated 9) was used here to constr...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lei, Cheng, Jishuai, Mou, Tangwei, Zhang, Ying, Xu, Xingli, Zhang, Jingjing, Li, Xueqi, Feng, Xiao, Xu, Xiangxiong, Liao, Yun, Fan, Shengtao, Wang, Lichun, Jiang, Guorun, Li, Qihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412103/
https://www.ncbi.nlm.nih.gov/pubmed/32708847
http://dx.doi.org/10.3390/v12070770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412103/
https://www.ncbi.nlm.nih.gov/pubmed/32708847
http://dx.doi.org/10.3390/v12070770

Ejemplares similares