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Poly-arginine-18 (R18) Confers Neuroprotection through Glutamate Receptor Modulation, Intracellular Calcium Reduction, and Preservation of Mitochondrial Function

Recent studies have highlighted that a novel class of neuroprotective peptide, known as cationic arginine-rich peptides (CARPs), have intrinsic neuroprotective properties and are particularly effective anti-excitotoxic agents. As such, the present study investigated the mechanisms underlying the ant...

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Detalles Bibliográficos
Autores principales: MacDougall, Gabriella, Anderton, Ryan S., Trimble, Amy, Mastaglia, Frank L., Knuckey, Neville W., Meloni, Bruno P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412265/
https://www.ncbi.nlm.nih.gov/pubmed/32610439
http://dx.doi.org/10.3390/molecules25132977