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Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses

Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host diversity. To take full advantage of the resoluti...

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Detalles Bibliográficos
Autores principales: Gibson, Keylie M., Steiner, Margaret C., Rentia, Uzma, Bendall, Matthew L., Pérez-Losada, Marcos, Crandall, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412389/
https://www.ncbi.nlm.nih.gov/pubmed/32674515
http://dx.doi.org/10.3390/v12070758