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Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses
Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host diversity. To take full advantage of the resoluti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412389/ https://www.ncbi.nlm.nih.gov/pubmed/32674515 http://dx.doi.org/10.3390/v12070758 |