Reducing YAP expression in Pkd1 mutant mice does not improve the cystic phenotype

The Hippo pathway is a highly conserved signalling route involved in organ size regulation. The final effectors of this pathway are two transcriptional coactivators, yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (WWTR1 or TAZ). Previously, we showed aberrant act...

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Detalles Bibliográficos
Autores principales: Formica, Chiara, Kunnen, Sandra, Dauwerse, Johannes G., Mullick, Adam E., Dijkstra, Kyra L., Scharpfenecker, Marion, Peters, Dorien J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412403/
https://www.ncbi.nlm.nih.gov/pubmed/32592332
http://dx.doi.org/10.1111/jcmm.15512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412403/
https://www.ncbi.nlm.nih.gov/pubmed/32592332
http://dx.doi.org/10.1111/jcmm.15512

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