Cargando…
Reducing YAP expression in Pkd1 mutant mice does not improve the cystic phenotype
The Hippo pathway is a highly conserved signalling route involved in organ size regulation. The final effectors of this pathway are two transcriptional coactivators, yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (WWTR1 or TAZ). Previously, we showed aberrant act...
Autores principales: | Formica, Chiara, Kunnen, Sandra, Dauwerse, Johannes G., Mullick, Adam E., Dijkstra, Kyra L., Scharpfenecker, Marion, Peters, Dorien J. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412403/ https://www.ncbi.nlm.nih.gov/pubmed/32592332 http://dx.doi.org/10.1111/jcmm.15512 |
Ejemplares similares
-
Characterisation of transcription factor profiles in polycystic kidney disease (PKD): identification and validation of STAT3 and RUNX1 in the injury/repair response and PKD progression
por: Formica, Chiara, et al.
Publicado: (2019) -
Polycystic Kidney Disease Caused by Bilineal Inheritance of Truncating PKD1 as Well as PKD2 Mutations
por: Losekoot, Monique, et al.
Publicado: (2020) -
Four‐jointed knock‐out delays renal failure in an ADPKD model with kidney injury
por: Formica, Chiara, et al.
Publicado: (2019) -
Detecting PKD1 variants in polycystic kidney disease patients by single‐molecule long‐read sequencing
por: Borràs, Daniel M., et al.
Publicado: (2017) -
Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice
por: Sousa, Marciana V., et al.
Publicado: (2021)