Synthesis and Antimicrobial Activity of Novel 4-Hydroxy-2-quinolone Analogs

Alkyl quinolone has been proven to be a privileged scaffold in the antimicrobial drug discovery pipeline. In this study, a series of new 4-hydroxy-2-quinolinone analogs containing a long alkyl side chain at C-3 and a broad range of substituents on the C-6 and C-7 positions were synthesized. The anti...

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Detalles Bibliográficos
Autores principales: Khamkhenshorngphanuch, Thitiphong, Kulkraisri, Kittipat, Janjamratsaeng, Alongkorn, Plabutong, Napasawan, Thammahong, Arsa, Manadee, Kanitta, Na Pombejra, Sarisa, Khotavivattana, Tanatorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412474/
https://www.ncbi.nlm.nih.gov/pubmed/32635479
http://dx.doi.org/10.3390/molecules25133059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412474/
https://www.ncbi.nlm.nih.gov/pubmed/32635479
http://dx.doi.org/10.3390/molecules25133059

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