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Targeting HIV-1 RNase H: N’-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants

HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant mutations. Therefore, a constant and timely effort is needed to identify new HIV-1 inhibitors active against drug-resistant variants. The ribo...

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Detalles Bibliográficos
Autores principales: Corona, Angela, Ballana, Ester, Distinto, Simona, Rogolino, Dominga, Del Vecchio, Claudia, Carcelli, Mauro, Badia, Roger, Riveira-Muñoz, Eva, Esposito, Francesca, Parolin, Cristina, Esté, José A., Grandi, Nicole, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412550/
https://www.ncbi.nlm.nih.gov/pubmed/32640577
http://dx.doi.org/10.3390/v12070729