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Targeting HIV-1 RNase H: N’-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants
HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant mutations. Therefore, a constant and timely effort is needed to identify new HIV-1 inhibitors active against drug-resistant variants. The ribo...
Autores principales: | Corona, Angela, Ballana, Ester, Distinto, Simona, Rogolino, Dominga, Del Vecchio, Claudia, Carcelli, Mauro, Badia, Roger, Riveira-Muñoz, Eva, Esposito, Francesca, Parolin, Cristina, Esté, José A., Grandi, Nicole, Tramontano, Enzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412550/ https://www.ncbi.nlm.nih.gov/pubmed/32640577 http://dx.doi.org/10.3390/v12070729 |
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