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TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway

BACKGROUND: The goal of the present study was to investigate the effects of TAK-242 on the gut microbiota and the TLR4/JAK2/STAT3 signaling pathway in mice with dextran sulfate sodium (DSS)-induced colitis. RESULTS: At the phylum level, Bacteroidetes, Firmicutes, Actinobacteria, Cyanobacteria, Epsil...

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Detalles Bibliográficos
Autores principales: Wang, Jiajia, Zhu, Guannan, Sun, Cheng, Xiong, Kangwei, Yao, Tingting, Su, Yuan, Fang, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412642/
https://www.ncbi.nlm.nih.gov/pubmed/32762699
http://dx.doi.org/10.1186/s12934-020-01417-x