Cargando…

TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway

BACKGROUND: The goal of the present study was to investigate the effects of TAK-242 on the gut microbiota and the TLR4/JAK2/STAT3 signaling pathway in mice with dextran sulfate sodium (DSS)-induced colitis. RESULTS: At the phylum level, Bacteroidetes, Firmicutes, Actinobacteria, Cyanobacteria, Epsil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jiajia, Zhu, Guannan, Sun, Cheng, Xiong, Kangwei, Yao, Tingting, Su, Yuan, Fang, Haiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412642/ https://www.ncbi.nlm.nih.gov/pubmed/32762699 http://dx.doi.org/10.1186/s12934-020-01417-x

Ejemplares similares

TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis
por: Liu, Sujie, et al.
Publicado: (2022)

Huanglian Jiedu Decoction ameliorates DSS-induced colitis in mice via the JAK2/STAT3 signalling pathway
por: Lu, Zhuo, et al.
Publicado: (2020)

TAK-242 ameliorates contact dermatitis exacerbated by IL-36 receptor antagonist deficiency
por: Fukushima, Hidehiko, et al.
Publicado: (2020)

Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice
por: Liu, Zhenzhen, et al.
Publicado: (2022)

TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats
por: Zhong, Xiang, et al.
Publicado: (2019)

Berberine-Loaded Carboxylmethyl Chitosan Nanoparticles Ameliorate DSS-Induced Colitis and Remodel Gut Microbiota in Mice
por: Zhao, Luqing, et al.
Publicado: (2021)

Mulberry Anthocyanins Ameliorate DSS-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Modulating Gut Microbiota
por: Mo, Jianling, et al.
Publicado: (2022)

Mesenchymal Stem Cells Ameliorate DSS-Induced Experimental Colitis by Modulating the Gut Microbiota and MUC-1 Pathway
por: Wang, Han, et al.
Publicado: (2023)

The Impact of Lactobacillus plantarum on the Gut Microbiota of Mice with DSS-Induced Colitis
por: Zhang, Fei, et al.
Publicado: (2019)

Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis
por: Larsen, Ida Søgaard, et al.
Publicado: (2021)

Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota
por: Yee, Su-Min, et al.
Publicado: (2023)

TAK-242 ameliorates epileptic symptoms in mice by inhibiting the TLR4/NF-κB signaling pathway
por: Dong, Jibo, et al.
Publicado: (2022)

Pretreatment with Bifidobacterium longum BAA2573 ameliorates dextran sulfate sodium (DSS)-induced colitis by modulating gut microbiota
por: Lin, Qiong, et al.
Publicado: (2023)

Sea Cucumber Peptides Ameliorate DSS-Induced Ulcerative Colitis: The Role of the Gut Microbiota, the Intestinal Barrier, and Macrophage Polarization
por: Yu, Song, et al.
Publicado: (2023)

Nuciferine Regulates Immune Function and Gut Microbiota in DSS-Induced Ulcerative Colitis
por: Zhu, Yiling, et al.
Publicado: (2022)

Ginger Alleviates DSS-Induced Ulcerative Colitis Severity by Improving the Diversity and Function of Gut Microbiota
por: Guo, Shanshan, et al.
Publicado: (2021)

PVA enema ameliorates DSS-induced acute colitis in mice
por: Zhang, Zhiyong, et al.
Publicado: (2023)

Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota
por: He, Ke-Jie, et al.
Publicado: (2022)

Shikimic Acid Regulates the NF-κB/MAPK Signaling Pathway and Gut Microbiota to Ameliorate DSS-Induced Ulcerative Colitis
por: Li, Xin, et al.
Publicado: (2023)

Lactobacillus ruminis Alleviates DSS-Induced Colitis by Inflammatory Cytokines and Gut Microbiota Modulation
por: Yang, Bo, et al.
Publicado: (2021)

Chimonanthus salicifolius extract alleviates DSS‐induced colitis and regulates gut microbiota in mice
por: Chen, Lin, et al.
Publicado: (2023)

Polyphenols from foxtail millet bran ameliorate DSS-induced colitis by remodeling gut microbiome
por: Yang, Ruipeng, et al.
Publicado: (2022)

Rubia cordifolia L. ameliorates DSS-induced ulcerative colitis in mice through dual inhibition of NLRP3 inflammasome and IL-6/JAK2/STAT3 pathways
por: Qin, Wei, et al.
Publicado: (2022)

Selective inhibition of Toll-like receptor 4 signaling by the small molecule TAK-242
por: Kawamoto, T, et al.
Publicado: (2006)

Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization
por: Li, Xiaoxia, et al.
Publicado: (2022)

Cyclic nigerosylnigerose ameliorates DSS-induced colitis with restoration of goblet cell number and increase in IgA reactivity against gut microbiota in mice
por: TSURUTA, Takeshi, et al.
Publicado: (2020)

Amelioration of AOM/DSS-Induced Murine Colitis-Associated Cancer by Evodiamine Intervention is Primarily Associated with Gut Microbiota-Metabolism-Inflammatory Signaling Axis
por: Wang, Mengxia, et al.
Publicado: (2021)

Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation
por: Guo, Fanghua, et al.
Publicado: (2021)

Terminalia bellirica Fruit Extract Alleviates DSS-Induced Ulcerative Colitis by Regulating Gut Microbiota, Inflammatory Mediators, and Cytokines
por: Li, Yao-Yao, et al.
Publicado: (2023)

Moringa oleifera Lam. Peptide Remodels Intestinal Mucosal Barrier by Inhibiting JAK-STAT Activation and Modulating Gut Microbiota in Colitis
por: Hong, Zi-Shan, et al.
Publicado: (2022)

The Toll-like receptor 4 antagonist TAK-242 protects against chronic pancreatitis in rats
por: Pan, Long-Fei, et al.
Publicado: (2017)

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity
por: Moser, V. Alexandra, et al.
Publicado: (2018)

Lactobacillus plantarum L15 Alleviates Colitis by Inhibiting LPS-Mediated NF-κB Activation and Ameliorates DSS-Induced Gut Microbiota Dysbiosis
por: Yu, Peng, et al.
Publicado: (2020)

Modified Gegen Qinlian Decoction Regulates Treg/Th17 Balance to Ameliorate DSS-Induced Acute Experimental Colitis in Mice by Altering the Gut Microbiota
por: Wang, Yifan, et al.
Publicado: (2021)

Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium
por: Zhang, Qianpeng, et al.
Publicado: (2016)

Maternal High Fat Diet Alters Gut Microbiota of Offspring and Exacerbates DSS-Induced Colitis in Adulthood
por: Xie, Runxiang, et al.
Publicado: (2018)

Capparis spinosa Alleviates DSS-Induced Ulcerative Colitis via Regulation of the Gut Microbiota and Oxidative Stress
por: Zhu, Xiaoting, et al.
Publicado: (2021)

Oenanthe javanica Ethanolic Extract Alleviates Inflammation and Modifies Gut Microbiota in Mice with DSS-Induced Colitis
por: Bae, Ui-Jin, et al.
Publicado: (2022)

Disturbance of lipid metabolism in germ-free mice transplanted with gut microbiota of DSS-induced colitis mice
por: Lee, Chungho, et al.
Publicado: (2023)

DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota
por: Zhao, Li-Ping, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_akjv23du5d8p00ol0jsf5qpjo3