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Sitagliptin improves functional recovery via GLP‐1R‐induced anti‐apoptosis and facilitation of axonal regeneration after spinal cord injury

Axon growth and neuronal apoptosis are considered to be crucial therapeutic targets against spinal cord injury (SCI). Growing evidences have reported stimulation of glucagon‐like peptide‐1 (GLP‐1)/GLP‐1 receptor (GLP‐1R) signalling axis provides neuroprotection in experimental models of neurodegener...

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Detalles Bibliográficos
Autores principales: Han, Wen, Li, Yao, Cheng, Jiangting, Zhang, Jing, Chen, Dingwen, Fang, Mingqiao, Xiang, Guangheng, Wu, Yanqing, Zhang, Hongyu, Xu, Ke, Wang, Hangxiang, Xie, Ling, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412681/
https://www.ncbi.nlm.nih.gov/pubmed/32573108
http://dx.doi.org/10.1111/jcmm.15501