Ageing‐associated increase in SGLT2 disrupts mitochondrial/sarcoplasmic reticulum Ca(2+) homeostasis and promotes cardiac dysfunction

The prevalence of death from cardiovascular disease is significantly higher in elderly populations; the underlying factors that contribute to the age‐associated decline in cardiac performance are poorly understood. Herein, we identify the involvement of sodium/glucose co‐transporter gene (SGLT2) in...

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Detalles Bibliográficos
Autores principales: Olgar, Yusuf, Tuncay, Erkan, Degirmenci, Sinan, Billur, Deniz, Dhingra, Rimpy, Kirshenbaum, Lorrie, Turan, Belma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412693/
https://www.ncbi.nlm.nih.gov/pubmed/32652890
http://dx.doi.org/10.1111/jcmm.15483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412693/
https://www.ncbi.nlm.nih.gov/pubmed/32652890
http://dx.doi.org/10.1111/jcmm.15483

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