Cargando…

CD73 acts as a prognostic biomarker and promotes progression and immune escape in pancreatic cancer

CD73 is a glycosylphosphatidylinositol (GPI)‐anchored protein that attenuates tumour immunity via cooperating with CD39 to generate immunosuppressive adenosine. Therefore, CD73 blockade has been incorporated into clinical trials for cancers based on preclinical efficacy. However, the biological role...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qiangda, Pu, Ning, Yin, Hanlin, Zhang, Jicheng, Zhao, Guochao, Lou, Wenhui, Wu, Wenchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412695/
https://www.ncbi.nlm.nih.gov/pubmed/32643277
http://dx.doi.org/10.1111/jcmm.15500