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Atorvastatin promotes bone formation in aged apoE(–/–) mice through the Sirt1–Runx2 axis

BACKGROUND: Statins are the most widely used drugs in elderly patients; the most common clinical application of statins is in aged hyperlipemia patients. There are few studies on the effects and mechanisms of statins on bone in elderly mice with hyperlipemia. The study is to examine the effects of a...

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Detalles Bibliográficos
Autores principales: Hong, Wei, Wei, Zhanying, Qiu, Zhaohui, Li, Zheng, Fu, Chensheng, Ye, Zhibin, Xu, Xiaoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412819/
https://www.ncbi.nlm.nih.gov/pubmed/32762716
http://dx.doi.org/10.1186/s13018-020-01841-0