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2-Hydroxypropyl-β-cyclodextrin blocks autophagy flux and triggers caspase-8-mediated apoptotic cascades in HepG2 cells

The cyclodextrin derivative, 2-Hydroxypropyl-β-cyclodextrin (HPβCD), from the cyclodextrin family is widely used as a drug carrier and offers promising strategies for treating neurodegenerative diseases and atherosclerosis regression. However, its side effects are not fully understood. Therefore, th...

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Detalles Bibliográficos
Autores principales: Sun, Haidong, Zong, Huajie, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413020/
https://www.ncbi.nlm.nih.gov/pubmed/32705246
http://dx.doi.org/10.3892/mmr.2020.11282