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Role of NKCC1 Activity in Glioma K(+) Homeostasis and Cell Growth: New Insights With the Bumetanide-Derivative STS66
Introduction: Na(+)-K(+)-2Cl(−) cotransporter isoform 1 (NKCC1) is important in regulating intracellular K(+) and Cl(−) homeostasis and cell volume. In this study, we investigated a role of NKCC1 in regulating glioma K(+) influx and proliferation in response to apoptosis inducing chemotherapeutic dr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413028/ https://www.ncbi.nlm.nih.gov/pubmed/32848856 http://dx.doi.org/10.3389/fphys.2020.00911 |