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Role of NKCC1 Activity in Glioma K(+) Homeostasis and Cell Growth: New Insights With the Bumetanide-Derivative STS66

Introduction: Na(+)-K(+)-2Cl(−) cotransporter isoform 1 (NKCC1) is important in regulating intracellular K(+) and Cl(−) homeostasis and cell volume. In this study, we investigated a role of NKCC1 in regulating glioma K(+) influx and proliferation in response to apoptosis inducing chemotherapeutic dr...

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Detalles Bibliográficos
Autores principales: Luo, Lanxin, Wang, Jun, Ding, Dawei, Hasan, Md Nabiul, Yang, Sung-Sen, Lin, Shih-Hua, Schreppel, Philipp, Sun, Baoshan, Yin, Yan, Erker, Thomas, Sun, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413028/
https://www.ncbi.nlm.nih.gov/pubmed/32848856
http://dx.doi.org/10.3389/fphys.2020.00911