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Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development

The generation of robust systemic and mucosal antibody and cell-mediated immune (CMI) responses that are protective, long-lasting, and can quickly be recalled upon subsequent re-exposure to the cognate antigen is the key to the development of effective vaccine candidates. These responses, whether th...

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Detalles Bibliográficos
Autores principales: Mani, Sachin, Toapanta, Franklin R., McArthur, Monica A, Qadri, Firdausi, Svennerholm, Ann-Mari, Devriendt, Bert, Phalipon, Armelle, Cohen, Daniel, Sztein, Marcelo B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413037/
https://www.ncbi.nlm.nih.gov/pubmed/31230883
http://dx.doi.org/10.1016/j.vaccine.2019.03.040