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Circular RNA cMTO1 Promotes PTEN Expression Through Sponging miR-181b-5p in Liver Fibrosis

BACKGROUND: Circular RNAs (circRNAs) are considered as key regulators of cancer biology. Recently, cMTO1 (a circRNA derived from MTO1 gene, hsa_circ_0007874) has been demonstrated to act as a tumor suppressor in hepatocellular carcinoma (HCC). However, the roles of cMTO1 in liver fibrosis are largel...

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Detalles Bibliográficos
Autores principales: Jin, Hui, Li, Chunxue, Dong, Peihong, Huang, Junting, Yu, Jinglu, Zheng, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413143/
https://www.ncbi.nlm.nih.gov/pubmed/32850833
http://dx.doi.org/10.3389/fcell.2020.00714