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Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement

The prevalence of diabetic metabolic derangement (DMetD) has increased dramatically over the last decades. Although there is increasing evidence that DMetD is associated with cardiac dysfunction, the early DMetD-induced myocardial alterations remain incompletely understood. Here, we studied early DM...

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Detalles Bibliográficos
Autores principales: Heinonen, Ilkka, Sorop, Oana, van Dalen, Bas M., Wüst, Rob C. I., van de Wouw, Jens, de Beer, Vincent J., Octavia, Yanti, van Duin, Richard W. B., Hoogstrate, Youri, Blonden, Lau, Alkio, Milla, Anttila, Katja, Stubbs, Andrew, van der Velden, Jolanda, Merkus, Daphne, Duncker, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413251/
https://www.ncbi.nlm.nih.gov/pubmed/32764569
http://dx.doi.org/10.1038/s41598-020-68637-4