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Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

Opticin is a class III member of the extracellular matrix small leucine-rich repeat protein/proteoglycan (SLRP) family found in vitreous humour and cartilage. It was first identified associated with the surface of vitreous collagen fibrils and several other SLRPs are also known to bind collagen fibr...

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Detalles Bibliográficos
Autores principales: Hansen, Uwe, Holmes, David F., Bruckner, Peter, Bishop, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413481/
https://www.ncbi.nlm.nih.gov/pubmed/32764753
http://dx.doi.org/10.1371/journal.pone.0234672