Cargando…
Dissection of α(4)β(7) integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β(7) antibodies
Integrin activation is associated with conformational regulation. In this study, we developed a system to evaluate conformational changes in α(4)β(7) integrin. We first inserted the PA tag into the plexin-semaphorin-integrin (PSI) domain of β(7) chain, which reacted with an anti-PA tag antibody (NZ-...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413538/ https://www.ncbi.nlm.nih.gov/pubmed/32764635 http://dx.doi.org/10.1038/s41598-020-70111-0 |