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Dissection of α(4)β(7) integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β(7) antibodies

Integrin activation is associated with conformational regulation. In this study, we developed a system to evaluate conformational changes in α(4)β(7) integrin. We first inserted the PA tag into the plexin-semaphorin-integrin (PSI) domain of β(7) chain, which reacted with an anti-PA tag antibody (NZ-...

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Detalles Bibliográficos
Autores principales:	Sato, Tsuyoshi, Ishihara, Sayaka, Marui, Ryoya, Takagi, Junichi, Katagiri, Koko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413538/ https://www.ncbi.nlm.nih.gov/pubmed/32764635 http://dx.doi.org/10.1038/s41598-020-70111-0

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