Cargando…

PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation

The therapeutic effect of irradiation is thought to come from DNA damage that affects rapidly proliferating cancer cells; however, resistant cells rapidly initiate mechanisms to repair such damage. While DNA repair mechanisms responsible for cancer cell survival following DNA damage are understood,...

Descripción completa

Detalles Bibliográficos
Autores principales: Montenegro, María F., González-Guerrero, Rebeca, Sánchez-del-Campo, Luis, Piñero-Madrona, Antonio, Cabezas-Herrera, Juan, Rodríguez-López, José Neptuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413540/
https://www.ncbi.nlm.nih.gov/pubmed/32764667
http://dx.doi.org/10.1038/s41598-020-70289-3