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Structure of the sodium-dependent phosphate transporter reveals insights into human solute carrier SLC20

Inorganic phosphate (P(i)) is a fundamental and essential element for nucleotide biosynthesis, energy supply, and cellular signaling in living organisms. Human phosphate transporter (hPiT) dysfunction causes numerous diseases, but the molecular mechanism underlying transporters remains elusive. We r...

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Detalles Bibliográficos
Autores principales: Tsai, Jia-Yin, Chu, Chen-Hsi, Lin, Min-Guan, Chou, Ying-Hsuan, Hong, Ruei-Yi, Yen, Cheng-Yi, Hsiao, Chwan-Deng, Sun, Yuh-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413737/
https://www.ncbi.nlm.nih.gov/pubmed/32821837
http://dx.doi.org/10.1126/sciadv.abb4024