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Molecular principles of assembly, activation, and inhibition in epithelial sodium channel
The molecular bases of heteromeric assembly and link between Na(+) self-inhibition and protease-sensitivity in epithelial sodium channels (ENaCs) are not fully understood. Previously, we demonstrated that ENaC subunits – α, β, and γ – assemble in a counterclockwise configuration when viewed from out...
Autores principales: | Noreng, Sigrid, Posert, Richard, Bharadwaj, Arpita, Houser, Alexandra, Baconguis, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413742/ https://www.ncbi.nlm.nih.gov/pubmed/32729833 http://dx.doi.org/10.7554/eLife.59038 |
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