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A Comprehensive Analysis of the Effect of SIRT1 Variation on the Risk of Schizophrenia and Depressive Symptoms

Depressive symptoms could be considered a mutual manifestation of major depressive disorder and schizophrenia. Rs3758391 is a functional locus of Sirtuin (SIRT1) involving depression etiology. In this study, we hypothesized that the SIRT1 SNP rs3758391 might be a hazard for schizophrenia pathogenesi...

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Detalles Bibliográficos
Autores principales: Wang, Dandan, Tang, Wei, Zhao, Junxiong, Fan, Weixing, Zhang, Yi, Zhang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413929/
https://www.ncbi.nlm.nih.gov/pubmed/32849821
http://dx.doi.org/10.3389/fgene.2020.00832