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iPSC-derived progenitor stromal cells provide new insights into aberrant musculoskeletal development and resistance to cancer in down syndrome

Down syndrome (DS) is a congenital disorder caused by trisomy 21 (T21). It is associated with cognitive impairment, muscle hypotonia, heart defects, and other clinical anomalies. At the same time, individuals with Down syndrome have lower prevalence of solid tumor formation. To gain new insights int...

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Detalles Bibliográficos
Autores principales: Galat, Yekaterina, Perepitchka, Mariana, Elcheva, Irina, Iannaccone, Stephen, Iannaccone, Philip M., Galat, Vasiliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414019/
https://www.ncbi.nlm.nih.gov/pubmed/32764607
http://dx.doi.org/10.1038/s41598-020-69418-9