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A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data

The phosphatidylinositol (PI) cycle is central to eukaryotic cell signaling. Its complexity, due to the number of reactions and lipid and inositol phosphate intermediates involved makes it difficult to analyze experimentally. Computational modelling approaches are seen as a way forward to elucidate...

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Detalles Bibliográficos
Autores principales: Mazet, Francoise, Tindall, Marcus J., Gibbins, Jonathan M., Fry, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414024/
https://www.ncbi.nlm.nih.gov/pubmed/32764630
http://dx.doi.org/10.1038/s41598-020-70215-7