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A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data
The phosphatidylinositol (PI) cycle is central to eukaryotic cell signaling. Its complexity, due to the number of reactions and lipid and inositol phosphate intermediates involved makes it difficult to analyze experimentally. Computational modelling approaches are seen as a way forward to elucidate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414024/ https://www.ncbi.nlm.nih.gov/pubmed/32764630 http://dx.doi.org/10.1038/s41598-020-70215-7 |