Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides

The use of non-standard toxicity models is a hurdle in the early development of antimicrobial peptides towards clinical applications. Herein we report an extensive in vitro and in vivo toxicity study of a library of 24 peptide-based antimicrobials with narrow spectrum activity towards veterinary pat...

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Detalles Bibliográficos
Autores principales: Greco, Ines, Molchanova, Natalia, Holmedal, Elin, Jenssen, Håvard, Hummel, Bernard D., Watts, Jeffrey L., Håkansson, Joakim, Hansen, Paul R., Svenson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414031/
https://www.ncbi.nlm.nih.gov/pubmed/32764602
http://dx.doi.org/10.1038/s41598-020-69995-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414031/
https://www.ncbi.nlm.nih.gov/pubmed/32764602
http://dx.doi.org/10.1038/s41598-020-69995-9

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