Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo

The present study involves the development of Dipivefrin hydrochloride (DV) containing Poloxamers (P407 and P188)-Carbopol-934 (CP) based thermoresponsive-gels for the management of elevated intraocular pressure (IOP). Optimal formulation was evaluated for gelation temperature (T(gel)), physicochemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkholief, Musaed, Kalam, Mohd Abul, Almomen, Aliyah, Alshememry, Abdullah, Alshamsan, Aws
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414100/
https://www.ncbi.nlm.nih.gov/pubmed/32792847
http://dx.doi.org/10.1016/j.jsps.2020.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414100/
https://www.ncbi.nlm.nih.gov/pubmed/32792847
http://dx.doi.org/10.1016/j.jsps.2020.07.001

Ejemplares similares