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Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo
The present study involves the development of Dipivefrin hydrochloride (DV) containing Poloxamers (P407 and P188)-Carbopol-934 (CP) based thermoresponsive-gels for the management of elevated intraocular pressure (IOP). Optimal formulation was evaluated for gelation temperature (T(gel)), physicochemi...
Autores principales: | Alkholief, Musaed, Kalam, Mohd Abul, Almomen, Aliyah, Alshememry, Abdullah, Alshamsan, Aws |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414100/ https://www.ncbi.nlm.nih.gov/pubmed/32792847 http://dx.doi.org/10.1016/j.jsps.2020.07.001 |
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