M-protein based vaccine induces immunogenicity and protection from Streptococcus pyogenes when delivered on a high-density microarray patch (HD-MAP)

We evaluated vaccination against Streptococcus pyogenes with the candidate vaccine, J8-DT, delivered by a high-density microarray patch (HD-MAP). We showed that vaccination with J8-DT eluted from a coated HD-MAP (J8-DT/HD-MAP), induced similar total IgG responses to that generated by vaccination wit...

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Detalles Bibliográficos
Autores principales: Mills, Jamie-Lee S., Jayashi Flores, Cesar M., Reynolds, Simone, Wun, Christine, Calcutt, Ainslie, Baker, S. Ben, Murugappan, Senthil, Depelsenaire, Alexandra C. I., Dooley, Jessica, Fahey, Paul V., Forster, Angus H., Pandey, Manisha, Good, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414110/
https://www.ncbi.nlm.nih.gov/pubmed/32802413
http://dx.doi.org/10.1038/s41541-020-00222-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414110/
https://www.ncbi.nlm.nih.gov/pubmed/32802413
http://dx.doi.org/10.1038/s41541-020-00222-2

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