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Impact of isolation methods on the biophysical heterogeneity of single extracellular vesicles

Extracellular vesicles (EVs) have raised high expectations as a novel class of diagnostics and therapeutics. However, variabilities in EV isolation methods and the unresolved structural complexity of these biological-nanoparticles (sub-100 nm) necessitate rigorous biophysical characterization of sin...

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Detalles Bibliográficos
Autores principales: Sharma, Shivani, LeClaire, Michael, Wohlschlegel, James, Gimzewski, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414114/
https://www.ncbi.nlm.nih.gov/pubmed/32770003
http://dx.doi.org/10.1038/s41598-020-70245-1