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A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

Sporadic Creutzfeldt-Jakob disease (sCJD) presents as a rapidly progressive dementia which is usually fatal within six months. No clinical blood tests are available for diagnosis or disease monitoring. Here, we profile blood microRNA (miRNA) expression in sCJD. Sequencing of 57 sCJD patients, and he...

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Detalles Bibliográficos
Autores principales: Norsworthy, Penny J., Thompson, Andrew G. B., Mok, Tze H., Guntoro, Fernando, Dabin, Luke C., Nihat, Akin, Paterson, Ross W., Schott, Jonathan M., Collinge, John, Mead, Simon, Viré, Emmanuelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414116/
https://www.ncbi.nlm.nih.gov/pubmed/32769986
http://dx.doi.org/10.1038/s41467-020-17655-x