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Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bones
In childhood medulloblastoma patients, the hedgehog antagonist vismodegib is an effective anti-cancer treatment but unfortunately induces irreversible growth arrests and growth impairment limiting its use in skeletally immature patients. We hypothesized that radial shock wave treatment (rSWT) may pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414117/ https://www.ncbi.nlm.nih.gov/pubmed/32770014 http://dx.doi.org/10.1038/s41598-020-69904-0 |