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Myeloid-derived suppressor cell depletion therapy targets IL-17A-expressing mammary carcinomas

Triple-negative breast cancer (TNBC) is an invasive subtype of breast cancer but paradoxically associated with increased tumor-infiltrating leukocytes. The molecular and cellular mechanisms underlying TNBC immunobiology are incompletely understood. Interleukin (IL)-17A is a pro-inflammatory cytokine...

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Detalles Bibliográficos
Autores principales: Dawod, Bassel, Liu, Jinghua, Gebremeskel, Simon, Yan, Chi, Sappong, Antonia, Johnston, Brent, Hoskin, David W., Marshall, Jean S., Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414122/
https://www.ncbi.nlm.nih.gov/pubmed/32770025
http://dx.doi.org/10.1038/s41598-020-70231-7