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NanoBRET binding assay for histamine H(2) receptor ligands using live recombinant HEK293T cells

Fluorescence/luminescence-based techniques play an increasingly important role in the development of test systems for the characterization of future drug candidates, especially in terms of receptor binding in the field of G protein-coupled receptors (GPCRs). In this article, we present the establish...

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Detalles Bibliográficos
Autores principales: Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther, Pockes, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414126/
https://www.ncbi.nlm.nih.gov/pubmed/32764682
http://dx.doi.org/10.1038/s41598-020-70332-3