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Enhancing the interpretability of transcription factor binding site prediction using attention mechanism

Transcription factors (TFs) regulate the gene expression of their target genes by binding to the regulatory sequences of target genes (e.g., promoters and enhancers). To fully understand gene regulatory mechanisms, it is crucial to decipher the relationships between TFs and DNA sequences. Moreover,...

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Detalles Bibliográficos
Autores principales: Park, Sungjoon, Koh, Yookyung, Jeon, Hwisang, Kim, Hyunjae, Yeo, Yoonsun, Kang, Jaewoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414127/
https://www.ncbi.nlm.nih.gov/pubmed/32770026
http://dx.doi.org/10.1038/s41598-020-70218-4