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Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation

Once described as mere “bags of enzymes,” bacterial cells are in fact highly organized, with many macromolecules exhibiting nonuniform localization patterns. Yet the physical and biochemical mechanisms that govern this spatial heterogeneity remain largely unknown. Here, we identify liquid–liquid pha...

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Detalles Bibliográficos
Autores principales: Ladouceur, Anne-Marie, Parmar, Baljyot Singh, Biedzinski, Stefan, Wall, James, Tope, S. Graydon, Cohn, David, Kim, Albright, Soubry, Nicolas, Reyes-Lamothe, Rodrigo, Weber, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414142/
https://www.ncbi.nlm.nih.gov/pubmed/32675239
http://dx.doi.org/10.1073/pnas.2005019117