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Cryo-EM structures of intact V-ATPase from bovine brain

The vacuolar-type H(+)-ATPases (V-ATPase) hydrolyze ATP to pump protons across the plasma or intracellular membrane, secreting acids to the lumen or acidifying intracellular compartments. It has been implicated in tumor metastasis, renal tubular acidosis, and osteoporosis. Here, we report two cryo-E...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Long, Tao, Hassan, Abdirahman, Wang, Jin, Sun, Yingyuan, Xie, Xiao-Song, Li, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414150/
https://www.ncbi.nlm.nih.gov/pubmed/32764564
http://dx.doi.org/10.1038/s41467-020-17762-9